| Date | Location | Result | |
| 03/26/23 | Louisville, Ky. (KFC Yum! Center) | #18 San Diego State 57, Creighton 56 | Box score |
| 03/24/23 | Louisville, Ky. (KFC Yum! Center) | Creighton 86, Princeton 75 | Box score |
| 03/19/23 | Denver, Colo. (Ball Arena) | Creighton 85, #11 Baylor 76 | Box score |
| 03/17/23 | Denver, Colo. (Ball Arena) | Creighton 72, NC State 63 | Box score |
| 03/10/23 | New York, N.Y. (Madison Square Garden) | #15 Xavier 82, Creighton 60 | Box score |
| 03/09/23 | New York, N.Y. (Madison Square Garden) | Creighton 87, Villanova 74 | Box score |
| 03/04/23 | Chicago, Ill. (Wintrust Arena) | Creighton 84, DePaul 70 | Box score |
| 03/01/23 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 99, Georgetown 59 | Box score |
| 02/25/23 | Philadelphia, Pa. (Wells Fargo Center) | Villanova 79, Creighton 67 | Box score |
| 02/21/23 | Omaha, Neb. (CHI Health Center Omaha) | #10 Marquette 73, Creighton 71 | Box score |
| 02/18/23 | Queens, NY (Carnesecca Arena) | Creighton 77, St. John's (NY) 67 | Box score |
| 02/14/23 | Providence, RI (Amica Mutual Pavilion) | #24 Providence 94, Creighton 86 (2OT) | Box score |
| 02/11/23 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 56, #21 Connecticut 53 | Box score |
| 02/08/23 | Newark, N.J. (Prudential Center) | Creighton 75, Seton Hall 62 | Box score |
| 02/04/23 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 66, Villanova 61 | Box score |
| 02/01/23 | Washington, DC (Capital One Arena) | Creighton 63, Georgetown 53 | Box score |
| 01/28/23 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 84, #13 Xavier 67 | Box score |
| 01/25/23 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 104, St. John's (NY) 76 | Box score |
| 01/17/23 | Indianapolis, Ind. (Hinkle Fieldhouse) | Creighton 73, Butler 52 | Box score |
| 01/14/23 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 73, #19 Providence 67 | Box score |
| 01/11/23 | Cincinnati, Ohio (Cintas Center) | #12 Xavier 90, Creighton 87 | Box score |
| 01/07/23 | Mansfield, CT (Harry A. Gampel Pavilion) | #4 UConn 69, Creighton 60 | Box score |
| 01/03/23 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 83, Seton Hall 61 | Box score |
| 12/25/22 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 80, DePaul 65 | Box score |
| 12/22/22 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 78, Butler 56 | Box score |
| 12/16/22 | Milwaukee, Wis. (Fiserv Forum) | Marquette 69, Creighton 58 | Box score |
| 12/12/22 | Las Vegas, Nev. (Michelob ULTRA Arena) | Arizona State 73, Creighton 71 | Box score |
| 12/10/22 | Las Vegas, Nev. (Michelob ULTRA Arena) | BYU 83, Creighton 80 | Box score |
| 12/04/22 | Omaha, Neb. (CHI Health Center Omaha) | Nebraska 63, Creighton 53 | Box score |
| 12/01/22 | Austin, Texas (Moody Center) | #2 Texas 72, Creighton 67 | Box score |
| 11/23/22 | Lahaina, HI (Lahaina Civic Center) | #14 Arizona 81, Creighton 79 | Box score |
| 11/22/22 | Lahaina, HI (Lahaina Civic Center) | Creighton 90, #9 Arkansas 87 | Box score |
| 11/21/22 | Lahaina, HI (Lahaina Civic Center) | Creighton 76, #21 Texas Tech 65 | Box score |
| 11/17/22 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 80, UC Riverside 51 | Box score |
| 11/14/22 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 94, Holy Cross 65 | Box score |
| 11/10/22 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 96, North Dakota 61 | Box score |
| 11/07/22 | Omaha, Neb. (CHI Health Center Omaha) | Creighton 72, St. Thomas 60 | Box score |