| Date | Location | Result | |
| 03-10-06 | Springfield, Mo. (Hammons Center) | Indiana State 73, Creighton 51 | Box score |
| 03-09-06 | Springfield, Mo. (Hammons Center) | Creighton 54, Southern Illinois 51 | Box score |
| 03-04-06 | Omaha, Neb. (Omaha Civic Auditorium) | Creighton 61, Northern Iowa 56 | Box score |
| 03-02-06 | Omaha, Neb. (Omaha Civic Auditorium) | Bradley 80, Creighton 63 | Box score |
| 02-26-06 | Normal, Ill. (Redbird Arena) | Illinois State 75, Creighton 61 | Box score |
| 02-24-06 | Terre Haute, Ind. (Hulman Center) | Indiana State 78, Creighton 58 | Box score |
| 02-19-06 | Omaha, Neb. (Omaha Civic Auditorium) | Evansville 78, Creighton 73 | Box score |
| 02-17-06 | Omaha, Neb. (Sapp Fieldhouse) | Southern Illinois 45, Creighton 44 | Box score |
| 02-12-06 | Omaha, Neb. (Omaha Civic Auditorium) | Drake 63, Creighton 62 | Box score |
| 02-04-06 | Wichita, Kan. (Charles Koch Arena) | Wichita State 82, Creighton 63 | Box score |
| 02-02-06 | Springfield, Mo. (Hammons Center) | Missouri State 70, Creighton 63 | Box score |
| 01-28-06 | Omaha, Neb. (Omaha Civic Auditorium) | Indiana State 79, Creighton 60 | Box score |
| 01-26-06 | Omaha, Neb. (Omaha Civic Auditorium) | Illinois State 71, Creighton 68 | Box score |
| 01-22-06 | Evansville, Ind. (Roberts Stadium) | Evansville 59, Creighton 46 | Box score |
| 01-19-06 | Carbondale, Ill. (SIU Arena) | Southern Illinois 85, Creighton 63 | Box score |
| 01-14-06 | Des Moines, Iowa (Knapp Center) | Drake 67, Creighton 52 | Box score |
| 01-09-06 | Omaha, Neb. (Omaha Civic Auditorium) | Creighton 78, Missouri State 57 | Box score |
| 01-07-06 | Omaha, Neb. (Omaha Civic Auditorium) | Creighton 93, Wichita State 83 | Box score |
| 12-31-05 | Peoria, Ill. (Robertson Field House) | Creighton 79, Bradley 68 | Box score |
| 12-29-05 | Cedar Falls, Iowa (West Gym) | Creighton 67, Northern Iowa 64 | Box score |
| 12-23-05 | Iowa City, Iowa (Carver-Hawkeye Arena) | Iowa 74, Creighton 64 | Box score |
| 12-21-05 | Lawrence, Kan. (Allen Fieldhouse) | Kansas 63, Creighton 52 | Box score |
| 12-19-05 | Omaha, Neb. (Omaha Civic Auditorium) | Kansas State 69, Creighton 59 | Box score |
| 12-10-05 | Albuquerque, N.M. (The Pit) | Louisiana Monroe 61, Creighton 60 | Box score |
| 12-09-05 | Albuquerque, N.M. (The Pit) | North Dakota State 68, Creighton 63 | Box score |
| 12-03-05 | Omaha, Neb. (Omaha Civic Auditorium) | Creighton 77, Colorado 72 | Box score |
| 11-30-05 | Omaha, Neb. (Omaha Civic Auditorium) | Creighton 76, Houston 59 | Box score |
| 11-21-05 | Lincoln, Neb. (Devaney Sports Center) | Nebraska 84, Creighton 50 | Box score |
| 11-19-05 | Evanston, Ill. (Welsh-Ryan Arena) | Northwestern 93, Creighton 77 | Box score |