| Date | Location | Result | |
| 03/20/21 | Rockford, Ill. | UNI 64, Creighton 63 | Box score |
| 03/19/21 | Rockford, Ill. | Creighton 72, Bowling Green 65 | Box score |
| 03/07/21 | Montville, Conn. (Mohegan Sun Arena) | Marquette 64, Creighton 59 | Box score |
| 03/06/21 | Montville, Conn. (Mohegan Sun Arena) | Creighton 83, Seton Hall 76 | Box score |
| 03/05/21 | Montville, Conn. (Mohegan Sun Arena) | Creighton 56, Georgetown 42 | Box score |
| 02/25/21 | Omaha, Neb. (D.J. Sokol Arena) | UConn 81, Creighton 49 | Box score |
| 02/22/21 | Milwaukee, Wis. (Al McGuire Arena) | Marquette 65, Creighton 41 | Box score |
| 02/20/21 | Chicago, Ill. (Wintrust Arena) | Creighton 83, DePaul 72 | Box score |
| 02/15/21 | Washington, D.C. (McDonough Arena) | Creighton 42, Georgetown 41 | Box score |
| 02/13/21 | South Orange, N.J. (Walsh Gymnasium) | Creighton 77, Seton Hall 76 (OT) | Box score |
| 02/10/21 | Omaha, Neb. (D.J. Sokol Arena) | Providence 60, Creighton 48 | Box score |
| 02/01/21 | Omaha, Neb. (D.J. Sokol Arena) | Marquette 66, Creighton 53 | Box score |
| 01/30/21 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 65, Georgetown 57 | Box score |
| 01/03/21 | Cincinnati, Ohio (Cintas Center) | Creighton 53, Xavier 50 | Box score |
| 12/22/20 | Omaha, Neb. (D.J. Sokol Arena) | DePaul 90, Creighton 81 | Box score |
| 12/19/20 | Bryn Mawr, Pa. (Finneran Pavillion) | Villanova 73, Creighton 68 | Box score |
| 12/17/20 | Mansfield, Conn. (Harry Gampel Pavilion) | UConn 80, Creighton 47 | Box score |
| 12/14/20 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 78, Nebraska 62 | Box score |
| 12/06/20 | Indianapolis, Ind. (Hinkle Fieldhouse) | Creighton 88, Butler 41 | Box score |
| 11/30/20 | Brookings, S.D. (Frost Arena) | South Dakota St. 66, Creighton 47 | Box score |
| 11/28/20 | Cedar Falls, Iowa (McLeod Center) | UNI 55, Creighton 52 | Box score |
| 11/25/20 | Omaha, Neb. (D.J. Sokol Arena) | Drake 75, Creighton 62 | Box score |