| Date | Location | Result | |
| 03/17/23 | Notre Dame, Ind. | Mississippi St. 81, Creighton 66 | Box score |
| 03/05/23 | Uncasville, Conn. (Mohegan Sun Arena) | Villanova 63, Creighton 61 | Box score |
| 03/04/23 | Uncasville, Conn. (Mohegan Sun Arena) | Creighton 75, Seton Hall 74 (OT) | Box score |
| 02/27/23 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 74, Butler 46 | Box score |
| 02/22/23 | Milwaukee, Wis. (Al McGuire Center) | Creighton 55, Marquette 44 | Box score |
| 02/18/23 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 75, Georgetown 34 | Box score |
| 02/15/23 | Mansfield, Conn. (Gampel Pavilion) | Connecticut 62, Creighton 60 | Box score |
| 02/12/23 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 73, Xavier 53 | Box score |
| 02/07/23 | South Orange, N.J. (Walsh Gymnasium) | Creighton 77, Seton Hall 64 | Box score |
| 02/04/23 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 81, St. John's (NY) 65 | Box score |
| 02/01/23 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 83, DePaul 74 | Box score |
| 01/28/23 | Washington, DC (McDonough Arena) | Creighton 65, Georgetown 57 | Box score |
| 01/24/23 | Providence, R.I. (Alumni Gymnasium) | Creighton 64, Providence 46 | Box score |
| 01/20/23 | Omaha, Neb. (D.J. Sokol Arena) | Villanova 73, Creighton 57 | Box score |
| 01/14/23 | Indianapolis, Ind. (Hinkle Fieldhouse) | Creighton 75, Butler 56 | Box score |
| 01/11/23 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 75, Seton Hall 53 | Box score |
| 01/08/23 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 68, Marquette 42 | Box score |
| 01/04/23 | Omaha, Neb. (D.J. Sokol Arena) | Providence 79, Creighton 75 | Box score |
| 12/31/22 | Chicago, Ill. (Wintrust Arena) | Creighton 92, DePaul 82 | Box score |
| 12/28/22 | Omaha, Neb. (D.J. Sokol Arena) | Connecticut 72, Creighton 47 | Box score |
| 12/20/22 | Stanford, Calif. (Maples Pavilion) | Stanford 72, Creighton 59 | Box score |
| 12/17/22 | Omaha, Neb. (D.J. Sokol Arena) | Arkansas 83, Creighton 75 | Box score |
| 12/10/22 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 75, Drake 71 | Box score |
| 12/04/22 | Queens, N.Y. (Carenesecca Arena) | St. John's (NY) 66, Creighton 62 | Box score |
| 12/02/22 | Villanova, Pa. (The Pavillion) | Creighton 67, Villanova 46 | Box score |
| 11/25/22 | Cincinnati, Ohio (Cintas Arena) | Creighton 57, Xavier 51 | Box score |
| 11/22/22 | Omaha, Neb. (Baxter Arena) | Creighton 93, Omaha 71 | Box score |
| 11/20/22 | Cedar Falls, Iowa (McLeod Center) | Creighton 85, UNI 66 | Box score |
| 11/15/22 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 77, Nebraska 51 | Box score |
| 11/10/22 | Vermillion, SD (Coyote Sanford Center) | Creighton 74, South Dakota 51 | Box score |
| 11/07/22 | Brookings, S.D. (Frost Arena) | Creighton 78, South Dakota State 69 | Box score |