| Date | Location | Result | |
| 03/22/25 | Austin, Texas (Moody Center) | Illinois 66, Creighton 57 | Box score |
| 03/10/25 | Uncasville, CT (Mohegan Sun Arena) | UConn 70, Creighton 50 | Box score |
| 03/09/25 | Uncasville, CT (Mohegan Sun Arena) | Creighton 73, Seton Hall 44 | Box score |
| 03/08/25 | Uncasville, CT (Mohegan Sun Arena) | Creighton 72, Georgetown 70 | Box score |
| 03/02/25 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 70, Villanova 55 | Box score |
| 02/27/25 | Hartford, Conn. (XL Center) | UConn 72, Creighton 53 | Box score |
| 02/23/25 | Chicago, Ill. (Wintrust Arena) | Creighton 83, DePaul 74 | Box score |
| 02/19/25 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 65, St. John's (NY) 62 | Box score |
| 02/15/25 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 70, Georgetown 48 | Box score |
| 02/08/25 | Villanova, PA (Finneran Pavillion) | Creighton 70, Villanova 57 | Box score |
| 02/05/25 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 72, Seton Hall 56 | Box score |
| 02/02/25 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 79, Providence 66 | Box score |
| 01/29/25 | Washington, DC (McDonough Arena) | Creighton 84, Georgetown 70 | Box score |
| 01/25/25 | Omaha, Neb. (CHI Health Center) | UConn 72, Creighton 61 | Box score |
| 01/22/25 | Indianapolis, Ind. (Hinkle Fieldhouse) | Creighton 63, Butler 52 | Box score |
| 01/18/25 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 92, DePaul 71 | Box score |
| 01/11/25 | South Orange, N.J. (Walsh Gymnasium) | Creighton 72, Seton Hall 64 | Box score |
| 01/08/25 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 71, Marquette 68 | Box score |
| 01/04/25 | Providence, R.I. (Alumni Hall/Mulaney) | Creighton 60, Providence 46 | Box score |
| 01/01/25 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 68, Butler 64 | Box score |
| 12/28/24 | Queens, N.Y. (Carnesecca Arena) | Creighton 75, St. John's (NY) 56 | Box score |
| 12/20/24 | San Francisco, Calif. (Chase Center) | #1 UCLA 70, Creighton 41 | Box score |
| 12/17/24 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 76, Wyoming 60 | Box score |
| 12/14/24 | Green Bay, Wis. (Kress Events Center) | Creighton 74, Green Bay 52 | Box score |
| 12/07/24 | Cedar Falls, Iowa (McLeod Center) | Creighton 75, UNI 71 | Box score |
| 12/04/24 | Cincinnati, Ohio (Cintas Center) | Creighton 82, Xavier 54 | Box score |
| 12/01/24 | Tulsa, Okla. (Reynolds Center) | Creighton 81, Tulsa 59 | Box score |
| 11/26/24 | Niceville, Fla. (Raider Arena) | Creighton 86, Syracuse 59 | Box score |
| 11/25/24 | Niceville, Fla (Raider Arena) | Creighton 91, Wichita State 63 | Box score |
| 11/22/24 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 80, #21 Nebraska 74 | Box score |
| 11/14/24 | Manhattan, Kan. (Bramledge Arena) | #10 Kansas State 86, Creighton 68 | Box score |
| 11/11/24 | Omaha, Neb. (D.J. Sokol Arena) | Creighton 80, Drake 72 | Box score |
| 11/08/24 | Brookings, S.D. (First Bank&Trust Arena) | South Dakota State 76, Creighton 71 | Box score |