| Date | Location | Result | |
| 10/28/21 | Indianapolis, Ind., | Butler 3, Creighton 1 | Box score |
| 10/24/21 | Omaha, Neb. | St. John's (NY) 3, Creighton 0 | Box score |
| 10/21/21 | Chicago, Ill. | DePaul 2, Creighton 0 | Box score |
| 10/17/21 | Omaha, Neb. | Creighton 2, Seton Hall 0 | Box score |
| 10/14/21 | Storrs, Conn. | UConn 3, Creighton 2 (2OT) | Box score |
| 10/10/21 | Villanova, Pa. | Villanova 2, Creighton 1 | Box score |
| 10/03/21 | Omaha, Neb. | Xavier 2, Creighton 0 | Box score |
| 09/30/21 | Omaha, Neb. | Marquette 1, Creighton 0 | Box score |
| 09/26/21 | Providence, R.I. | Providence 1, Creighton 0 (OT) | Box score |
| 09/23/21 | Omaha, NE | Georgetown 1, Creighton 1 (2OT) | Box score |
| 09/16/21 | Ames, Iowa | Iowa State 1, Creighton 0 | Box score |
| 09/12/21 | Kansas City, Mo. | Creighton 3, Kansas City 0 | Box score |
| 09/09/21 | Omaha, Neb. | Creighton 2, North Dakota St. 0 | Box score |
| 09/05/21 | Omaha, Neb. | Creighton 3, South Dakota St. 0 | Box score |
| 09/02/21 | Omaha, Neb. | South Dakota 0, Creighton 0 (2OT) | Box score |
| 08/29/21 | Tulsa, Okla. | Creighton 3, Oral Roberts 0 | Box score |
| 08/26/21 | Tulsa, Okla. | Tulsa 1, Creighton 0 | Box score |
| 08/22/21 | Omaha, Neb. | Creighton 2, Drake 0 | Box score |
| 08/19/21 | Omaha, Neb. | Creighton 2, Montana 1 (2OT) | Box score |