| Date | Location | Result | |
| 12-04-10 | Minneapolis, Minn. | Minnesota 3, Creighton 0 (25-19,30-28,25-20) | Box score |
| 12-03-10 | Minneapolis, Minn. | Creighton 3, Iowa State 2 (27-25,16-25,25-23,19-25,15-11) | Box score |
| 11-27-10 | Cedar Falls, Iowa | Northern Iowa 3, Creighton 1 (25-18,25-19,20-25,25-20) | Box score |
| 11-26-10 | Cedar Falls, Iowa | Creighton 3, Wichita State 1 (25-21,25-19,17-25,25-12) | Box score |
| 11-25-10 | Cedar Falls, Iowa | Creighton 3, Drake 1 (25-11,21-25,25-18,25-18) | Box score |
| 11-20-10 | Omaha, Neb. | Creighton 3, Southern Illinois 1 (28-26,25-13,26-28,25-15) | Box score |
| 11-19-10 | Omaha, Neb. | Creighton 3, Evansville 0 (25-20,25-15,25-16) | Box score |
| 11-13-10 | Omaha, Neb. | Creighton 3, Drake 0 (25-15,25-15,25-18) | Box score |
| 11-06-10 | Springfield, Mo. | Missouri State 3, Creighton 0 (25-20,25-19,25-23) | Box score |
| 11-05-10 | Wichita, Kan. | Wichita State 3, Creighton 2 (25-21,20-25,25-17,21-25,15-13) | Box score |
| 10-30-10 | Omaha, Neb. | Creighton 3, Illinois State 1 (25-21,25-27,25-17,25-14) | Box score |
| 10-29-10 | Omaha, Neb. | Creighton 3, Indiana State 0 (25-21,25-16,25-18) | Box score |
| 10-23-10 | Cedar Falls, Iowa | Northern Iowa 3, Creighton 0 (27-25,27-25,25-19) | Box score |
| 10-22-10 | Peoria, Ill. | Creighton 3, Bradley 0 (25-12,25-19,25-11) | Box score |
| 10-16-10 | Des Moines, Iowa | Drake 3, Creighton 1 (25-19,25-22,23-25,25-22) | Box score |
| 10-09-10 | Omaha, Neb. | Creighton 3, Wichita State 2 (25-22,17-25,22-25,25-18,15-12) | Box score |
| 10-08-10 | Omaha, Neb. | Creighton 3, Missouri State 2 (25-14,23-25,25-23,16-25,15-10) | Box score |
| 10-02-10 | Terre Haute, Ind. | Creighton 3, Indiana State 0 (25-22,25-10,25-7) | Box score |
| 10-01-10 | Normal, Ill. | Creighton 3, Illinois State 1 (20-25,25-17,25-19,25-23) | Box score |
| 09-25-10 | Omaha, Neb. | Creighton 3, Bradley 1 (25-9,18-25,25-10,25-16) | Box score |
| 09-24-10 | Omaha, Neb. | Northern Iowa 3, Creighton 1 (25-16,25-21,24-26,25-20) | Box score |
| 09-18-10 | Evansville, Ind. | Creighton 3, Evansville 0 (25-20,25-16,25-20) | Box score |
| 09-17-10 | Carbondale, Ill. | Creighton 3, Southern Illinois 0 (26-24,25-22,25-20) | Box score |
| 09-11-10 | Milwaukee, Wis. | Creighton 3, Central Michigan 1 (25-17,22-25,26-24,25-23) | Box score |
| 09-10-10 | Milwaukee, Wis. | Creighton 3, Marquette 0 (25-21,25-23,26-24) | Box score |
| 09-10-10 | Milwaukee, Wis. | Toledo 3, Creighton 2 (21-25,26-24,25-15,23-25,15-13) | Box score |
| 09-04-10 | St. Louis, Mo. | Creighton 3, Wake Forest 0 (25-20,25-18,25-19) | Box score |
| 09-04-10 | St. Louis, Mo. | Iowa 3, Creighton 2 (25-19,25-20,20-25,19-25,20-18) | Box score |
| 09-03-10 | St. Louis, Mo. | Creighton 3, Saint Louis 0 (25-22,25-18,25-21) | Box score |
| 08-31-10 | Omaha, Neb. | Nebraska 3, Creighton 0 (26-24,25-18,25-15) | Box score |
| 08-28-10 | Omaha, Neb. | Kansas 3, Creighton 1 (25-21,27-29,25-14,25-22) | Box score |
| 08-28-10 | Omaha, Neb. | Lipscomb 3, Creighton 1 (20-25,25-22,28-26,25-21) | Box score |
| 08-27-10 | Omaha, Neb. | Creighton 3, San Francisco 1 (25-19,25-20,24-26,25-23) | Box score |